Important Safety Information

Differin^® Lotion, 0.1%, Differin^® Gel, 0.3% and Epiduo^® Gel are indicated for the topical treatment of acne vulgaris in patients 12 years and older. Apply to affected skin once per day avoiding the eyes, lips and mucous membranes. The most common side effects associated with the use of Differin^® products and Epiduo^® Gel are redness, scaling, dryness, stinging and burning. With Epiduo^® Gel, you may also experience contact dermatitis and/or skin irritation. Most adverse events reported while using these products were mild to moderate in severity, occurred early in treatment and decreased thereafter, but speak to your doctor if they persist. You should avoid excessive exposure to sunlight and sunlamps while using Epiduo^® Gel or Differin^® products, and using sunscreen products and protective clothing is recommended. Do not use irritating topical products that contain resorcinol, salicylic acid or sulfur during treatment and do not apply these products to areas that have been depilated with waxed products. These products have not been tested in pregnant or nursing women, or with the elderly. All products are designated Pregnancy Category C.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.